Treatment of UTI: Not All Drugs Created Equal
“For uncomplicated bladder infections, cefpodoxime (Vantin) may not be a viable antibiotic alternative to fluoroquinolone ciprofloxacin (Cipro, Proquin), a randomized trial suggested.
More women needed further treatment after a short course of the cephalosporin than after the same duration of ciprofloxacin (clinical cure rate 82% versus 93%), Thomas M. Hooton, MD, of the University of Miami, and colleagues found.
The difference didn’t meet criteria for noninferiority (P=0.57), the researchers reported in the February 8 issue of the Journal of the American Medical Association.
Fluoroquinolones are considered the most reliable for treating urinary infections, but the search has been on for other, effective antimicrobials in this setting because of rising resistance to fluoroquinolones, the group explained.”
http://www.medpagetoday.com/Urology/Urology/31084
